3 min read
What is nattokinase? An explanation of the mechanism of action, side effects, and contraindications of nattokinase
Olivia Davis
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Diets Premium Expert • 24.09.2026
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Scientifically reviewed by a clinical dietitian:
This article has been peer-reviewed for adherence to IŻŻ, WHO, and PTGiP clinical nutritional standards.
| Diets Premium Expert Olivia Davis | min read 3 min | Scientifically reviewed by a clinical dietitian 24.09.2026 |
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Key Takeaways
In the sales world, sales are crucial, so manufacturers persuade us to purchase products regardless of their impact on health. In most grocery stores, you can find soy milk, soy protein, soybean oil, and even soy soap, but soy in various forms may not be the best choice due to the GMO content. Fermentation, on the other hand, provides the body with essential nutrients and is the safest form of consumption. However, is nattokinase safe to consume and what are its potential side effects?
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Nattokinase
Natto is a form of soy food, traditionally consumed in Japan. The key to its health benefits is fermentation. It is made by soaking soy, steaming it, and then adding Bacillus subtilis bacteria to it. Its taste and smell does not convince everyone, but its texture resembles sticky, durable, small beans, and its smell is noticeable ammonia. Although it does not make a good first impression, its content should make you want to try it.
Nattokinase is active
One of the reasons why this product does not cause gastrointestinal discomfort is that it is produced during the fermentation process of nattokinase, used for various medicinal purposes. This enzyme has a safer and stronger action than aspirin. It supports normal blood circulation, its viscosity, density and blood pressure, it also helps to maintain normal circulation mechanisms.
Nattokinase is contraindicated, side effects
No adverse effects of nattokinase have been reported, but due to the small number of studies in this area, caution should be exercised when using the supplement and not exceed the amount recommended by the manufacturer. Further studies are also needed to prove the absence of interaction with other medicines. In order to prevent possible bleeding, this specificity should be taken into account primarily by people taking blood thinners such as warfarin. Therefore, before starting supplements, it is advisable to consult a doctor.
Olivia Davis
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Diets Premium team expert. Specializes in nutrition plans, strength sports, and training plans.
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