Clinical Nutrition Strategies in Intensive Care, Advanced Malignancy, and Palliative Oncology
| Diets Premium Expert Wojciech Wiśniewski | min read 3 min | Scientifically reviewed by a clinical dietitian 23.10.2026 |
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Nutritional failure constitutes a paramount clinical challenge both within Intensive Care Units (ICU) and throughout advanced oncological and palliative trajectories. Both settings are characterized by profound metabolic derangements driven by systemic pro-inflammatory cytokine storms, severe protein hypercatabolism, and anabolic resistance. Disease-related malnutrition and cancer cachexia severely compromise clinical outcomes, blunt antineoplastic treatment tolerance, and escalate mortality. Crucially, therapeutic paradigms diverge based on clinical goals: in acute critical illness, interventions focus on organ preservation and metabolic stabilization, whereas in terminal palliative care, the mandate shifts entirely toward comfort preservation, symptom relief, and clinical ethics. This review evaluates ESPEN guidelines for clinical nutrition across this intensive-palliative spectrum.
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Nutritional treatment in the intensive care unit
Nutritional treatment in palliative care
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Wojciech Wiśniewski
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