Non-Alcoholic Fatty Liver Disease – Diagnosis, Treatment, Diet
Emilia Szymańska
2026-03-23
6 min. read
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Non-alcoholic fatty liver disturbance (NAFLD) is increasingly common among non-drinkers in developing countries, affecting up to 25% of the global population. In Poland, approximately 15% of the population suffers from this disorder. It is noticeably more frequently diagnosed in individuals from various age and social groups, including children and adolescents.
Non-alcoholic fatty liver disease (NAFLD): Clinical definition, features, and symptomatic presentation
Non-alcoholic fatty liver disease (NAFLD) represents a pathological condition characterized by the excessive intrahepatic accumulation of lipids—primarily triglycerides—within hepatocytes. Under normal physiological conditions, hepatic fat content should not exceed 5% of the organ’s total mass; surpassing this threshold constitutes hepatic steatosis. The overwhelming majority of individuals diagnosed with NAFLD concurrently present with abdominal obesity, insulin resistance or overt type 2 diabetes mellitus, and dyslipidemia of varying severity. The clinical course of NAFLD is frequently asymptomatic or marked by non-specific manifestations, which may include persistent fatigue, generalized malaise, diminished physical performance, sleep architecture disturbances, dull pain localized to the right upper quadrant, and palmar erythema (reddening of the palms). Observed symptoms may also stem from coexisting metabolic disorders, thereby complicating definitive diagnostic assessment
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