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Less Familiar, Yet Effective Joint Supplements
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Table of Contents 8
While the joint connections in the human body exhibit exceptional resistance to damage, unfortunately, every micro-injury contributes to a gradual deterioration of the joints.
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Cissus quadrangularis
We commence our compilation with an exotic plant known as Cissus quadrangularis. Systematically, we categorize it as a group of succulents, organisms that function similarly to cacti. In African and Far Eastern folk medicine, it has long been employed as a remedy for alleviating ailments resulting from injuries or accidents. The mechanism of action of this plant primarily revolves around inhibiting the action of substances that promote inflammation, such as cyclo- and lipoxygenase. Cissus quadrangularis stimulates anabolic pathways responsible for the stimulation of bone mineralization and regeneration. Furthermore, it significantly decreases the amount of pro-inflammatory cytokines, which contribute to the activation of bone-destructive processes. Unfortunately, there is a lack of sufficient studies and scientific research that confirm the full efficacy of Cissus quadrangularis, which hinders the complete confirmation of all benefits associated with supplementation of this component.
02 / 08
Tree known as Boswellia serrata, native to India
This is another specimen of a tree that originates from India and is utilized in the prevention of diseases and injuries to the musculature. Initially, Boswellia serrata was employed in the production of incense, however, it was discovered over time that its extract could be effectively utilized to protect the joints from inflammatory processes. Specifically, the boswellic acids found in this plant are characterized by an extremely potent anti-inflammatory effect.
03 / 08
Bromelain - a collection of proteolytic enzymes present in pineapple
Bromelain is a complex set of proteolytic enzymes that occur in pineapple. This commonly used substance is considered a means of facilitating the digestibility and absorption of proteins in our body. Therefore, it is often recommended as an aid in the treatment of dyspepsia, a condition commonly referred to as indigestion. However, bromelain does not solely deal with digestive issues. Evidence of this is the improvement of microcirculation, the reduction of inflammatory states, or the acceleration of wound healing.
04 / 08
Dimethyl Sulphon – MSM
Hidden under the abbreviation MSM is organic sulfur, known as methylsulfonylmethane, which is one of the most popular micronutrients in food. Unfortunately, the structure of this sulfur is very delicate and prone to destruction during thermal processing or storage of food. Sulfur is also essential for life, as it is involved in the synthesis of glutathione, one of the endogenous and most important antioxidants in the body. However, our main interest lies in the application of dimethyl sulfur in the treatment of diseases and problems related to the musculoskeletal system. MSM is one of the main preventive measures for this group of pathologies, as organic sulfur compounds inhibit the breakdown of collagen and support its production. MSM also allows for more effective production of keratin, which is essential for maintaining healthy skin, hair, and nails. In addition, the combination of sulfur with chondroitin and glucosamine has a positive effect on the regeneration and nutrition process of joint cartilage, increasing the elasticity of our joint connections and improving their durability. It is also worth mentioning that sulfur is essential in reducing inflammation, as it increases the elasticity and permeability of cell membranes, leading to a reduction in pressure within the edema and a significant reduction in its size.
05 / 08
Ginger
Ginger is indisputably one of the most popular spices in our kitchen, yet its therapeutic properties remain largely unrecognized. Although it is primarily associated with symptoms such as nausea and other digestive issues, it turns out that ginger can also be utilized to mitigate problems related to the musculoskeletal system. This is due to the presence of a substance known as gingerol, which exhibits exceptionally potent anti-inflammatory properties.
06 / 08
Turmeric
Turmeric, a primary component of Indian curry mix, shares potent anti-inflammatory properties with ginger. The main functional compound of turmeric, curcumin, plays a pivotal role in limiting the accumulation of a protein called beta-amyloid. This protein is a primary cause of degenerative diseases and joint pain, as it transforms into harmful deposits in our bodies. Combining turmeric and ginger with honey is recommended due to their significant impact on the inflammation process, specifically in inhibiting the release of compounds known as eicosanoids, which promote the buildup of pro-inflammatory prostaglandins.
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Quercetin, also recognized as quercetol, is a naturally occurring constituent in numerous plants.
Quercetin is a highly effective antioxidant found in products such as red onions, apple peels, grapes, and popular chia seeds. Quercetin assists in significant reduction of inflammation symptoms and restores optimal body functioning.
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Unsaturated fatty acid compounds
Our abridged list includes a group of fatty compounds that are widely acknowledged by all who care about their health. Omega 3-6-9 acids not only have a beneficial impact on our hormonal-lipid economy and the protection of our circulatory system, but also influence the condition of our motor system. Why? Primarily, fat compounds are one of the fundamental building blocks of all cell structures in the human body, including bone cells. Furthermore, fatty acids allow for appropriate moistening of joint surfaces, which significantly contributes to limiting their degradation and protecting against early wear.
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Scientifically reviewed by a clinical dietitian
• 22.03.2026
Laura Schneider
Diets Premium Expert
Diets Premium team expert. Specializes in nutrition plans, strength sports, and training plans.
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PubMed Clinical Guidelines
